FIGURE

Fig. 1

ID

ZDB-FIG-150413-22

Publication

Gu et al., 2015 - Defective apical extrusion signaling contributes to aggressive tumor hallmarks

Other Figures

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Fig. 1

(A) S1P₂ immunoblot of HBE cells expressing control (left) or S1P₂-specific shRNA (right) with α-tubulin as loading control. (B) Representative images of HBE cells (DNA only) expressing control (left) or S1P₂-specific shRNA (right) grown for 3 weeks. Scale bar, 10 µm. (C) Proliferation assay indicates that S1P₂-knockdown cells proliferate at the same rate as wild type controls cells. (D) Representative DIC micrographs of 5-dpf WT (top) and Mil (S1P₂ mutant) (bottom) zebrafish larvae, where cartoon shows region where fish was imaged. Scale bars, 100 µm where red box indicates region imaged. (E) Quantification of epidermal clumps of 22 zebrafish larvae.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	s1pr2^m93/m93
Observed In:	epidermal cell
Stage:	Day 5

Phenotype Detail

Acknowledgments

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