FIGURE

Fig. 6

ID

ZDB-FIG-150325-40

Publication

Kenyon et al., 2015 - Zebrafish Rab5 Proteins and a role for Rab5ab in nodal signalling

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Fig. 6

The role of rab5ab in ventral gene expression. Expression of wnt8a in (A) control injected embryos (n=27/27), (B) rab5ab MO injected embryos (n=29/29) and (C) rab5ab RNA injected embryos (n=41/42) at 30% epiboly. Expression of bmp4 in (D) control injected embryos (n=17/17), (E) rab5ab MO injected embryos (n=27/27) and (F) rab5ab RNA injected embryos (n=20/20) at 30% epiboly. Expression of vox in (G) control injected embryos (n=47/47), (H) rab5ab MO injected embryos (n=32/32) and (I) rab5ab RNA injected embryos (n=55/55) at 30% epiboly. Expression of bmp2b in (J) control injected embryos (n=41/41), (K) rab5ab MO injected embryos (n=36/36) and (L) rab5ab RNA injected embryos (n=41/41) at 30% epiboly. All embryos shown are animal view.

Expression Data

Genes:	bmp2b bmp4 vox wnt8a
Fish:	WT WT + MO1-rab5ab
Knockdown Reagent:	MO1-rab5ab
Anatomical Terms:	margin whole organism dorsal-most region whole organism ventral region
Stage:	30%-epiboly

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 397(2), Kenyon, E.J., Campos, I., Bull, J.C., Williams, P.H., Stemple, D.L., Clark, M.D., Zebrafish Rab5 Proteins and a role for Rab5ab in nodal signalling, 212-24, Copyright (2015) with permission from Elsevier. Full text @ Dev. Biol.