FIGURE

Fig. 7

ID

ZDB-FIG-150204-625

Publication

Wu et al., 2014 - Nuclear Receptor Subfamily 2 Group F Member 1a (nr2f1a) Is Required for Vascular Development in Zebrafish

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Fig. 7

nr2f1a is required for the growth of ISV cells.

(A-D) TUNEL labeling and AO staining was used to detect apoptotic cells in wild type, and nr2f1a^e2i2 morphants. Although some apoptotic cells were observed on the skin, cell death in vascular regions was not elevated compared to wild type controls. (E-H) The number of cells forming each ISV counted in wild type control Tg(kdrl:mCherry; fli1a:negfp)^y7 (E) and nr2f1a morphant embryos (F) at 32 hpf. (G) Proportional distribution of ISVs containing 1-5 cells and (H) average ISV cells per ISV counted in both wild type and nr2f1a morphant. (*** refers to p<0.0001 by an unpaired student’s t-test).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO3-nr2f1a ci5Tg; y7Tg + MO3-nr2f1a
Knockdown Reagent:	MO3-nr2f1a
Observed In:	intersegmental vessel endothelial cell trunk apoptotic process
Stage:	Prim-15

Phenotype Detail

Acknowledgments

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