Fig. S5

Convergent extension movements are not affected by knockdown of smp, Related to Figure 1. (A) wnt5b expression in the marginal zone of mismatch control embryos. (B) Similar expression of wnt5b in smp morphant (antisense) embryos. (C) wnt11 expression in the body axis of mismatch controls. (D) smp morphants show similar expression of wnt11 in the body axis. (E) Mismatch-control embryos were injected with CMTPX cell tracker dye into the upper marginal zone at 50% epiboly as shown by lateral view. (E′) Dorsal view of a mismatch-control embryo showing labeled cells throughout the embryonic body axis. (F) smp morphant embryos (lateral view) were similarly injected with CMTPX cell tracker dye at 50% epiboly. (F′) Dorsal view of CMTPX-positive cells align at the midline and cluster at the anterior region at tailbud stage similar to the mismatch control embryos. (G) Expression of no tail (ntl) (black arrows) in the posterior and calpthesin L (hgg) (white arrows) in the anterior of the mismatch control embryos. (H) Expression of ntl and hgg in smp morphants is similar to controls. Scale bars in A-F′ are 100 μm.