Fig. 5
- ID
- ZDB-FIG-150115-24
- Publication
- Imai et al., 2014 - Stem-loop binding protein is required for retinal cell proliferation, neurogenesis, and intraretinal axon pathfinding in zebrafish
- Other Figures
- All Figure Page
- Back to All Figure Page
The rw440 mutant gene encodes SLBP. (A) Nonsense mutation occurs in 3-Glutamic acid (E) of the slbp1 gene. RNA-binding domain (RBD) is indicated. (B) Western blot of wild-type and rw440 mutant embryos using anti-histone H3 (top) and anti-α-tubulin antibody (middle). The amount of histone H3 and α-tubulin is decreased in the rw440 mutant at 2 dpf and 3 dpf respectively. The western blot membrane is stained with Coomassie Brilliant Blue (bottom), indicating that the loading amount is the same for each lane. (C) Evolutionary tree of SLBP proteins. (D) Expression of zebrafish slbp1 mRNA. The slbp1 mRNA is expressed in the eight-cell stage, and prominently expressed in the head, including the retina and the tectum at 24 hpf. The slbp1 mRNA expression is gradually restricted in the retinal CMZ (arrowheads), and in the peripheral rim of the optic tectum. (E) Expression of zebrafish slbp2 mRNA. The slbp2 mRNA expression is detected in the eight cell stage, but not after 31 hpf. tc, optic tectum. |
| Genes: | |
|---|---|
| Fish: | |
| Anatomical Terms: | |
| Stage Range: | 8-cell to Protruding-mouth |
Reprinted from Developmental Biology, 394(1), Imai, F., Yoshizawa, A., Matsuzaki, A., Oguri, E., Araragi, M., Nishiwaki, Y., Masai, I., Stem-loop binding protein is required for retinal cell proliferation, neurogenesis, and intraretinal axon pathfinding in zebrafish, 94-109, Copyright (2014) with permission from Elsevier. Full text @ Dev. Biol.