FIGURE

Fig. 5

ID

ZDB-FIG-140728-6

Publication

Mathews et al., 2014 - Mutation of 3-hydroxy-3-methylglutaryl CoA synthase I reveals requirements for isoprenoid and cholesterol synthesis in oligodendrocyte migration arrest, axon wrapping, and myelin gene expression

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Fig. 5

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Expression Data

Genes:	EGFP mbpa plp1a
Fish:	WT hmgcs1^vu57/vu57 (AB) vu12Tg vu16Tg hmgcs1^vu57/vu57; vu12Tg hmgcs1^vu57/vu57; vu16Tg
Conditions:	chemical treatment: drug chemical treatment: GGTI-2133 chemical treatment: lonafarnib
Anatomical Terms:	hindbrain oligodendrocyte oligodendrocyte cytoplasm oligodendrocyte plasma membrane spinal cord oligodendrocyte spinal cord ventral region
Stage Range:	Protruding-mouth to Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT hmgcs1^vu57/vu57 (AB) vu12Tg vu16Tg hmgcs1^vu57/vu57; vu12Tg hmgcs1^vu57/vu57; vu16Tg
Conditions:	chemical treatment: drug chemical treatment: GGTI-2133 chemical treatment: lonafarnib
Observed In:	dorsal longitudinal fasciculus hindbrain oligodendrocyte oligodendrocyte development oligodendrocyte differentiation protein farnesylation protein geranylgeranylation spinal cord central nervous system myelination spinal cord oligodendrocyte
Stage Range:	Protruding-mouth to Day 4

Phenotype Detail

Acknowledgments

Full text @ J. Neurosci.