FIGURE
Fig. 6
- ID
- ZDB-FIG-140512-24
- Publication
- Osborn et al., 2014 - Loss of FTO antagonises Wnt signaling and leads to developmental defects associated with ciliopathies
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Fig. 6
E15.5 Fto knockout mice embryos display tissue specific cilia defects. Paraffin sections from wild type and mutant animals showing immunolocalization of acetylated- α-tubulin (green) and γ-tubulin or IFT88 (red) in the choroid plexus (A,B); nasopharynx (C); cochlea (D); kidney (E). Loss of Fto results in shortened cilia in the choroid plexus, nasopharynx and kidney whilst cilia in the cochlea appear unperturbed. Scale bars: in A, B 50 μm; in C,D,E 20 μm. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
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