FIGURE

Fig. 3

ID

ZDB-FIG-140422-3

Publication

Perathoner et al., 2014 - Bioelectric signaling regulates size in zebrafish fins

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

The alf phenotype is due to gain-of-function mutations within the K⁺ channel kcnk5b.

(A) alf mutations map to chromosome 20 between z11841 and z21067. Gray: north markers; blue: south markers. (B) Electropherogram of kcnk5b at position 169 and 241 in mutants and wild type siblings. (C) The amino acids affected in the mutants are well conserved among vertebrates. (D) A revertant of alf^dty86d (j131x8) shows wild type-sized fins. (E) kcnk5b^j131x8 fish harbor an intragenic deletion in kcnk5b that is predicted to cause a truncated protein lacking three transmembrane (TM) domains.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	kcnk5b^{j131x8/j131x8} (AB)
Observed In:	fin
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Genet.