FIGURE
Fig. 3
- ID
- ZDB-FIG-140321-22
- Publication
- Chen et al., 2001 - Analysis of the zebrafish smoothened mutant reveals conserved and divergent functions of hedgehog activity
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Fig. 3
Essential and conserved role of vertebrate smo in Hh signaling. (A,B) Lateral view of wild-type and mutant embryos at 24 hpf (A) and 12 hpf (B) demonstrating the absence of ptc1 expression in the mutants. (C-E) ptc-1 expression in response to manipulation of Hh signaling components in wild-type and mutant embryos indicates a conserved role of smo in the pathway in zebrafish. Embryos were injected at one- to two-cell stages and ptc1 expression is determined at 12 hpf. (C) shh mRNA injection. (D) twhh mRNA injection. (E) PKI mRNA injection. Arrows indicate ectopic expression. |
Expression Data
| Gene: | |
|---|---|
| Fish: | |
| Anatomical Term: | |
| Stage Range: | 5-9 somites to Prim-5 |
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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