FIGURE
Fig. 8
- ID
- ZDB-FIG-140114-33
- Publication
- Wilkins et al., 2013 - p53-Mediated Biliary Defects Caused by Knockdown of cirh1a, the Zebrafish Homolog of the Gene Responsible for North American Indian Childhood Cirrhosis
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Fig. 8
Biliary defects in Cirhin-deficient larvae are abrogated by tp53 mutation. (A) Brightfield (left column) and fluorescent (right column) images of representative 5 dpf wild-type Cirhin-deficient larvae (BODIPY-FL C16 assay). Arrows indicate position of gallbladder. (B) Brightfield (left column) and fluorescent (right column) images of representative 5 dpf tp53-mutant Cirhin-deficient larvae (BODIPY-FL C16 assay). Arrows indicate position of gallbladder. (C) Quantitation of gallbladder fluorescence in Cirhin-deficient larvae. *, p<0.05 vs Tu mismatch MO-injected 1 ng; #, p<0.05 vs Tu cirh1a IE14 MO-injected 1 ng. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Knockdown Reagent: | |
| Observed In: | |
| Stage: | Day 5 |
Phenotype Detail
Acknowledgments
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