FIGURE

Fig. 7

ID

ZDB-FIG-140107-50

Publication

Reichert et al., 2013 - A BMP regulatory network controls ectodermal cell fate decisions at the neural plate border

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Fig. 7

A two-step model for zebrafish ectodermal patterning. Step 1 depicts the DV gradient present during gastrulation. High BMP activity is observed ventrally as generated by bmp2b/4/7a ligand expression and reinforced by Cvl2. BMP activity is inhibited dorsally by expression of the diffusible antagonists Chordin and Noggin. Prospective PPE and NC are formed at intermediate levels of BMP signalling. In step 2 the initial gradient has reshaped into distinct BMP activity domains during neurulation. The regulatory network is depicted. Components in black act positively, whereas those in red act negatively. NC, neural crest; PPE, preplacodal ectoderm.

Expression Data

Gene:	mRFP
Fish:	cj100Tg
Anatomical Terms:	ectoderm whole organism ventral side
Stage Range:	75%-epiboly to 5-9 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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