FIGURE

Fig. 10

ID

ZDB-FIG-131029-39

Publication

Novikov et al., 2013 - Tmem88a mediates GATA-dependent specification of cardiomyocyte progenitors by restricting WNT signaling

Other Figures

All Figure Page

Back to All Figure Page

Fig. 10

CP formation is repressed by forced expression of wild-type but not mutant tmem88a, and this phenotype is rescued by enhancing early WNT signaling. (A-E) WISH for nkx2.5 (box) and ntl in representative 8-somite stage uninjected control zebrafish embryos (A, Ctrl), embryos injected with wild-type tmem88a mRNA (B, 88a RNA), embryos injected with mutated tmem88a mRNA (C, Δ88a), heat-shocked uninjected control embryos (D, Ctrl+wnt8), and heat-shocked embryos that had been injected with wild-type tmem88a mRNA (E, 88a RNA+wnt8). Heat-shock treatment was administered to embryos at 3 hpf for 30 minutes. n>15 embryos analyzed per condition. (F) nkx2.5 relative expression levels assessed by qPCR. ^**P<0.01; error bars indicate s.d.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development