FIGURE

Fig. 4

ID

ZDB-FIG-131024-11

Publication

Kamel et al., 2013 - Requirement for frzb and fzd7a in cranial neural crest convergence and extension mechanisms during zebrafish palate and jaw morphogenesis

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Fig. 4

frzb and fzd7a are required for palatal extension. Anterior is to the left in all views. (A–F) Photoconversion was performed unilaterally, with the contralateral side serving as internal control. Wildtype trabeculae/maxillary prominence was photoconverted at 55 hpf and followed through 4.5 dpf, where the paired maxillary process CNCCs converge in the midline (asterisk) and extend (bracket) with distal proliferative front (bar). In frzb and fzd7a morphants, paired maxillary process converged in the midline (asterisk in E, F) but failed to extend (brackets in E and F are shorter than in D) and the proliferative domain is diminished in the distal portion of the palate (bars in E and F are shorter than in D).

Expression Data

Gene:	Kaede
Fish:	zf393Tg zf393Tg + MO2-fzd7a zf393Tg + MO3-frzb
Knockdown Reagents:	MO2-fzd7a MO3-frzb
Anatomical Term:	neurocranial trabecula
Stage Range:	Long-pec to Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	zf393Tg + MO2-fzd7a zf393Tg + MO3-frzb
Knockdown Reagents:	MO2-fzd7a MO3-frzb
Observed In:	neurocranial trabecula
Stage:	Day 4

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 381(2), Kamel, G., Hoyos, T., Rochard, L., Dougherty, M., Tse, W., Shubinets, V., Grimaldi, M., and Liao, E.C., Requirement for frzb and fzd7a in cranial neural crest convergence and extension mechanisms during zebrafish palate and jaw morphogenesis, 423-33, Copyright (2013) with permission from Elsevier. Full text @ Dev. Biol.