FIGURE

Fig. S5

ID

ZDB-FIG-130516-49

Publication

Espín et al., 2013 - TNF receptors regulate vascular homeostasis through a caspase-8, caspase-2 and P53 apoptotic program that bypasses caspase-3

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Fig. S5

Confirmation of the vascular defects promoted by genetic depletion of TNFRSF1B using a DN mutant form. (A) Representative embryo injected with 200 ng/egg DN TNFRSF1B (right panel) showed impaired differentiation of the caudal artery (CA) and caudal vein (CV). Note the interruption of the CA (arrow) and blood pooling in the altered CV (asterisks). A control larva injected with 200 ng/egg antisense mRNA is shown on the left panel for comparison. Scale bars, 500 μm. (C) The vascular defects shown in (A) were scored at 72 hpf as indicated in the legend to Figure 2. ***P<0.0001 according to Chi-square contingency test.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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