FIGURE

Fig. S6

ID

ZDB-FIG-130411-3

Publication

Boglev et al., 2013 - Autophagy induction is a tor- and tp53-independent cell survival response in a zebrafish model of disrupted ribosome biogenesis

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Fig. S6

Absence of dead cells in the intestinal lumen of WT and tti^s450 larvae at 7 dpf. (A–F) Transmission electron micrographs of transverse sections of WT and tti^s450 larvae at 168 hpf (7 dpf). The number of conspicuous autophagosome-like structures in the IECs of tti^s450 larvae has diminished by 7 dpf and there are no dead cells in the lumen (D). Meanwhile, liver cells of tti^s450 larvae contain abundant autolysosome-like structures at this time-point (F, white arrows). Scale bars = 50 μm (A, B); 10 µm (C–F). ib, intestinal bulb; n, nucleus; m, mitochondria; mv, microvilli; l, liver; bd, bile duct; a, arteriole.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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