FIGURE

Fig. 1

ID

ZDB-FIG-121102-29

Publication

Matsui et al., 2012 - Celf1 regulation of dmrt2a is required for somite symmetry and left-right patterning during zebrafish development

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Fig. 1

Overexpression of celf1 leads to defects in bilateral symmetry of the somites. (A-C) Representative images of uncx4.1 expression demonstrating symmetric (mRFP; A), left-biased (Celf1; B) or right-biased (Celf1; C) asymmetric somitogenesis in zebrafish embryos at 12-14 hpf. Dorsal view, anterior to the top. Asterisks mark the last-formed somite. (D) Percentages of symmetric (L=R), left-biased (L>R) or right-biased (L<R) asymmetric somitogenesis in mRFP- (n=60), celf1-(n=89) or celf1^Δ^linker- (n=60) overexpressing embryos. (E-G) Representative images of her1 expression demonstrating symmetric (mRFP; E) or asymmetric (Celf1; F,G) oscillation in embryos at 12-14 hpf. Arrows indicate the position of the anterior strip of her1. Vegetal pole view. (H) Percentages of symmetric and asymmetric her1 oscillation in mRFP- (n=87), celf1-(n=98) or celf1^Δ^linker- (n=76) overexpressing embryos. Scale bars: 200 μm.

Expression Data

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Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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