FIGURE

Fig. S4

ID

ZDB-FIG-121029-7

Publication

Ni et al., 2012 - Conditional control of gene function by an invertible gene trap in zebrafish

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Fig. S4

Hepatocyte-specific Cre activity in hepatocyte-Cre embryos. (A) Double carriers of hepatocyte-Cre/Tg(eab2:[EGFP-T-mCherry]) were imaged at 5 dpf. Expression of the red fluorescent protein mCherry indicates Cre activity. (B–D) Hepatocyte-Cre does not rescue defects in intestinal epithelium. At 5 dpf, the intestinal epithelium in wild-type larvae is polarized and well organized with little cell death (B). In contrast, the intestinal epithelium in supv3l1^GtT/GtT mutants is disorganized with no apparent apical–basal polarity and abundant cell death (arrows) (C). Despite rescue of mature hepatocytes, the intestinal epithelium in supv3l1^LKO mutant is still disorganized with no apparent apical–basal polarity and abundant cell death (arrows) (D).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA