FIGURE

Fig. 7

ID

ZDB-FIG-121026-22

Publication

Hsu et al., 2012 - Cdc42 GTPase and Rac1 GTPase act downstream of p120 catenin and require GTP exchange during gastrulation of zebrafish mesoderm

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Fig. 7

Wild-type Rac1 mRNA (WT-Rac1 mRNA) rescues 90% of the &dger1 splice-MO knockdown of p120 catenin δ1. A: Representative 16-somite embryos side views, dorsal up, anterior left, uninjected, and injected with δ1 splice-MO (Sp-MO) and WT-Rac1 mRNA as indicated. B: Summary of the distance between the head and tailbud as marked with arrows in A. C: Side views with dorsal left of Prim 5 stage embryos uninjected and injected as indicated. D: Summary of average length-to-width ratio of the yolk extension of embryos at the Prim 5 stage treated as in (C). E: Summary of the differences in post-anal tail extension of Prim 5 embryos treated similarly to C. F: Percent normal Prim 5 to Prim 15 embryos without gastrulation defects when injected with Sp-MO and/or WT-Rac1 as indicated. Error bars represent the s.e.m for 5 to 118 embryos as indicated on the bars in B, D, and E. Scale bars in A and C = 200 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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