Fig. 7
- ID
- ZDB-FIG-120720-17
- Publication
- Harden et al., 2012 - Close association of olfactory placode precursors and cranial neural crest cells does not predestine cell mixing
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Neural crest cells migrate with olfactory placode precursors. Images from time lapse movie showing migration of cranial neural crest cells (CNCCs; green) and olfactory placode (OP) precursors (red). A: At 10s (somite stage), OP precursors (red) are wrapped around the rostral end of the neural tube (asterisk). B: At 12s, the OP precursors move away from the rostral midline (asterisk) as CNCCs (green) advance rostrally. C: By 14s, the CNCCs start to surround the posterior edge of the OP precursors. D: The OP precursors (red) are no longer evident at the tip of the neural tube at 16s. CNCCs (green) arrive at the anterior limit of the OPs. E: At 18s, the CNCCs (green) have migrated to the rostral limit of the olfactory placodes. The posterior region of the OP contains neither green nor red cells (white outline), which is the presumed region of dlx3b expression. F: At the end of the movie (20s), the olfactory placodes are fully formed. All images are dorsal views with rostral to the left. Scale bar = 30 μm (see S3, S4 for movies). |