FIGURE

Fig. 4

ID

ZDB-FIG-120525-56

Publication

Zhang et al., 2012 - beta-Catenin 1 and beta-catenin 2 play similar and distinct roles in left-right asymmetric development of zebrafish embryos

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Fig. 4

Knockdown of ctnnb1 and ctnnb2 in DFCs perturbs spaw and Nodal-regulated gene expression. Embryos at the 512-cell stage were injected. (A-L) Representative images show different patterns of spaw expression at about the 23-somite stage. The spaw domain in the left or right LPM is indicated by black or red arrows, respectively. Note that spaw expression was absent in the anterior LPM of DFC^β-cat2MO embryos. (M-O) Representative images of pitx2c expression in 23-somite stage embryos. The pitx2c domain in the left or right posterior LPM is indicated by black or red arrows, respectively. Scale bars: 100 μm. (P) Statistical data for spaw in the LPM, lft1 in the diencephalon, lft2 in the heart primordium and pitx2c in the posterior LPM at the 23-somite stage.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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