Fig. 1

Chd7 expression patterns during zebrafish embryogenesis.

Chd7 was expressed ubiquitously throughout the embryo during epiboly (A), at the 4 somite stage (B), and at the 8 somite stage (C). (D) At the 13 somite stage, expression remained relatively ubiquitous, but with stronger expression noted within the retina and at the perimeters of developed somites. (E) At the 18 somite stage, tissue-specific expression was observed in the eyes, brain, somites, and tailbud. This expression pattern remained through 24 hours post fertilization (F). (E2) No staining occurred when hybridized with a chd7 sense probe. (G) At 48 hours post fertilization, chd7 expression began to diminish from the body of the zebrafish but remained in the eye and in the brain. e, eye; ep, eye primordium; mb, midbrain; hp, head primordium; s, somite; t, tail; tb, tailbud; y, yolk; ye, yolk extension.