Fig. 7

Mutants involving retinal degeneration associated with a general pigmentation defect. Mutant individuals (lower) are shown next to their wild-type siblings (upper). (A,B,C) piegus(pgu)^m286. (D,E,F) punktata(pkt)^m288. (G,H,I) mizerny(miz)^m293. All three mutants have abnormal melanocytes and reduced eye size. Sections through mutant retinae at 3 dpf (C,I) and 5 dpf (F) reveal an excessive amount of cell death. (J,K,L) Higher magnification of the dorsal retina in the wild type (J), pgu^m286 (K) and miz^m293 (L). Cell corpses appear as small, round, intensely staining particles (arrows in K and L). In pkt^m288 and miz^m293 the photoreceptor cell layer has abnormal appearance (F,I). A, D and G show lateral views; B, E and H dorsal views. The dorsal side is oriented up in panels showing lateral views or sections. In panels showing head phenotypes anterior is left. All sections are transverse.