Fig. 6

Examples of mutant phenotypes from the categories of Growth retardation and Nonspecific retinal degeneration. Mutant individuals (lower) are shown next to their wild-type siblings (upper). (A,B,C) out of sight (out)^m233. (D,E,F) turbulent (tub)^m125. (G,H,I) zimny (zny)^m419. (A,B) The eye of out^m233 is substantially reduced at 3 dpf. (C) All retinal laminae are present and cell death in excess of wild-type levels is not observed in out^m233 at this stage. At 5 dpf mutants tub^m125 (D,E) and zny^m419(G,H) are characterized by a reduced eye size and somewhat abnormal brain shape. Cell death is extensive in both tub^m125 (F) and zny^m419(I) retinae at 3 dpf. Cell corpses appear as small, round, intensely staining particles (F). Retinal patterning defects are inconsistent in this group of mutants. A, D and G show lateral views; B, E and H dorsal views. The dorsal side is oriented up in panels showing lateral views or sections. In panels showing head phenotypes anterior is left. All sections are transverse.