FIGURE

Fig. 7

ID

ZDB-FIG-120131-16

Publication

Pan et al., 2012 - Robo2 determines subtype-specific axonal projections of trigeminal sensory neurons

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Fig. 7

Morphogenesis of subtype-specific branch growth and synaptogenesis. (A) Multi-time point imaging was performed in segments 9-11 (boxed area), where the innervation pattern differs most between Trpa1b and Isl1SS neurons. (B) Fluorescent images of individual trigeminal sensory neuron afferents imaged from 2 to 4 dpf. Representative examples are shown for Trpa1b (left column), Isl1SS (middle) and Isl1SS in robo2^-/- (right) zebrafish. Red arrowheads point to branches. (C-E) Afferent morphology is compared between genotypes (wild type versus robo2^-/- in the Isl1SS subtype) and subtypes (Trpa1b versus Isl1SS). Error bars indicate s.e.m. ^**, P<0.01; ^***, P<0.001. Scale bar: 50 μm.

Expression Data

Genes:	EGFP Kaede
Fish:	a128Tg a129Tg robo2^{ti272z/ti272z}; a128Tg
Anatomical Terms:	trigeminal ganglion axon trigeminal ganglion sensory neuron
Stage Range:	Long-pec to Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	robo2^{ti272z/ti272z}; a128Tg
Observed In:	collateral sprouting in absence of injury trigeminal ganglion axon trigeminal ganglion axon collateral
Stage Range:	Protruding-mouth to Day 5

Phenotype Detail

Acknowledgments

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