FIGURE

Fig. 7

ID

ZDB-FIG-111117-29

Publication

Korzh et al., 2011 - The interaction of epithelial Ihha and mesenchymal Fgf10 in zebrafish esophageal and swimbladder development

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Fig. 7

Endodermal phenotype of dae^tbvbo mutant. A, B, Expression of fgfr2 in the gut and swimbladder at 74 hpf. A, Whole mount. B, Cross section, expression of fgfr2 is in the epithelium of esophagus and pneumatic duct. C, D, Whole mount, expression of ihha in dae^-/- mutant and control. C¹, D¹, Yolk is removed and expression of ihha shows reduced epithelium of esophagus, gastrointestinal tract and swimbladder compared to control larvae. E, F, Expression of shha shows reduced epithelium of esophagus and swimbladder in dae^-/- mutant compared to control larvae. G, H Swimbladder epithelium in dae^-/- mutant is faintly reduced compared to control at 50 hpf. I, % of mean diameter of esophageal epithelium in position of arrows in dae^-/- mutant compared to control in figure G, H, J, % of mean distance between the white bars delineated swimbladder epithelium in the figure G and H reduced in dae^-/- mutant. Anterior to the left. Abbreviations: es, esophagus; g, gut; p, endocrine pancreas; pd, pneumatic duct; s, somite; sb, swimbladder; nt, neural tube. Scale bars: 250 μm.

Expression Data

Genes:	fgfr2 ihha mnx1 shha
Fish:	AB fgf10a^tbvbo/tbvbo
Anatomical Terms:	endocrine pancreas esophageal epithelium esophagus gut pneumatic duct epithelium swim bladder swim bladder bud
Stage Range:	Long-pec to Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	fgf10a^tbvbo/tbvbo
Observed In:	esophageal epithelium swim bladder epithelium
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 359(2), Korzh, S., Winata, C.L., Zheng, W., Yang, S., Yin, A., Ingham, P., Korzh, V., and Gong, Z., The interaction of epithelial Ihha and mesenchymal Fgf10 in zebrafish esophageal and swimbladder development, 262-76, Copyright (2011) with permission from Elsevier. Full text @ Dev. Biol.