FIGURE

Fig. 3

ID

ZDB-FIG-111013-19

Publication

Liu et al., 2003 - Cadherin-1, -2, and -11 expression and cadherin-2 function in the pectoral limb bud and fin of the developing zebrafish

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Fig. 3

Embryos injected with cdh2 morpholino antisense oligonucleotides (cdh2MO) phenocopy the pac and the glass onion mutants. A–E: Views from 24 hours postfertilization (hpf) embryos with anterior to the left and dorsal up. B illustrates defects in the midbrain and hindbrain (H). The arrows in A and B point to the midbrain–hindbrain boundary. The arrowhead in B points to loose cell aggregates in the fourth ventricle. Compared with the tip of the tail in control embryos (C), cdh2MO embryos had split fin (D) or tail blister (E). F,G: Cross-sections (dorsal is up) of Cdh2 immunostaining of control morpholino oligonucleotide (Control) -injected (F) and cdh2MO-injected embryos (G), both at 50 hpf. dm, dorsal musculature; ed, endoskeletal disc; Lb, limb bud; vm, ventral musculature.

Expression Data

Gene:	cdh2
Antibody:	Ab1-cdh2
Fish:	WT WT + MO1-cdh2 + MO2-cdh2
Knockdown Reagents:	MO1-cdh2 MO2-cdh2
Anatomical Terms:	hindbrain pectoral fin bud cartilage element pectoral fin bud myoblast
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-cdh2 + MO2-cdh2
Knockdown Reagents:	MO1-cdh2 MO2-cdh2
Observed In:	cranial nerve II fourth ventricle fourth ventricle cell hindbrain hindbrain fourth ventricle midbrain midbrain fourth ventricle pectoral fin development
Stage Range:	Prim-5 to Long-pec

Phenotype Detail

Acknowledgments

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