FIGURE

Fig. 3

ID

ZDB-FIG-110428-4

Publication

Tse et al., 2011 - The deubiquitylating enzyme Cops6 regulates different developmental processes during early zebrafish embryogenesis

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Fig. 3

Phenotypes of cops6 morphants. cops6 morphants in an AB wild-type background showed dorsalized phenotypes at different stages: (B) 12-14 somite, (E) prim-5 and (H) long-pec. They all showed the reduced development of the posterior part, which is a feature of dorsalization. C3 and C4 dorsalized phenotypes are shown in (E,H). The dorsalized phenotype caused by cops6 knockdown was rescued by coinjection of cops6 mRNA with MO (C,F,I). More than 80% of dorsalized embryos were rescued back to a phenotype similar to wild-type, while the remaining ones showed a much milder phenotype, C1, in (F,I). Scale bar: 100 μm (A,B), 120 μm (C), 80 μm (D), 150 μm (E,F,I), 90 μm (G) and 135 μm (H).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO1-cops6
Knockdown Reagent:	MO1-cops6
Observed In:	whole organism
Stage Range:	10-13 somites to Long-pec

Phenotype Detail

Acknowledgments

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