FIGURE

Fig. 4

ID

ZDB-FIG-110407-4

Publication

Padanad et al., 2011 - Pax2/8 proteins coordinate sequential induction of otic and epibranchial placodes through differential regulation of foxi1, sox3 and fgf24

Other Figures

All Figure Page

Back to All Figure Page

Fig. 4

Misexpression of foxi1 inhibits otic development. (A, B) Expression of pax2a at 14 hpf in a control embryo (A) and a hs:foxi1 transgenic embryo (B) heat shocked at 11 hpf. (C, D) Expression of pax2a at 14 hpf in a mosaic embryo as seen under bright field (C) and fluorescence imaging (D). The mosaic was produced by transplanting lineage-labeled hs:foxi1 transgenic cells (green fluorescence) into a non-transgenic host. The embryo was heat shocked at 11 hpf to activate the transgene. Note the absence of pax2a expression in transgenic cells (white arrows). Images show dorsal views with anterior to the top (A–B); lateral views with anterior to the left (C–D). Scale bar, 50 μm (A, B), 25 μm (C, D).

Expression Data

Gene:	pax2a
Fish:	AB x19Tg/+
Condition:	heat shock
Anatomical Term:	otic placode
Stage:	10-13 somites

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	x19Tg/+
Condition:	heat shock
Observed In:	otic placode
Stage:	10-13 somites

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 351(1), Padanad, M.S., and Riley, B.B., Pax2/8 proteins coordinate sequential induction of otic and epibranchial placodes through differential regulation of foxi1, sox3 and fgf24, 90-98, Copyright (2011) with permission from Elsevier. Full text @ Dev. Biol.