FIGURE

Fig. 1

ID

ZDB-FIG-110407-38

Publication

Carvalho et al., 2011 - A high-throughput screen for tuberculosis progression

Other Figures

All Figure Page

Back to All Figure Page

Fig. 1

Outcome of M. marinum yolk sac injection of embryos between the 16- and the 512-cell stage.

(A) 5 dpi fli1-egfp larva with gfp-labelled vasculature showing spread of bacteria (red) throughout the body (scale bar: 250 μm). (B and D) Bright-field/fluorescence overlay and (C and E) confocal z-stack of red-fluorescent bacteria showing activation of green-fluorescent gags at the (B and C) edge of the yolk extension and on the (D and E) tail of a 7 day-old larva (scale bar: 25 μm). (F and H) Bright-field confocal plane and (G and I) confocal z-stack of red-fluorescent bacteria co-localizing with green-fluorescent leukocytes detected by L-plastin immunostaining (scale bar: 25 μm). The lesions caused by the granulomas can be clearly seen in F and H.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	slc45a2^unspecified; y1Tg
Condition:	bacterial treatment by injection: Mycobacterium marinum E11
Observed In:	granuloma formation
Stage:	Days 7-13

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One