FIGURE

Fig. 4

ID

ZDB-FIG-110207-37

Publication

Tehrani et al., 2011 - Antagonistic interactions of hedgehog, Bmp and retinoic acid signals control zebrafish endocrine pancreas development

Other Figures

All Figure Page

Back to All Figure Page

Fig. 4

Decreased Hh signaling leads to increased numbers of RA-induced pdx1-expressing cells. (A-D) Dorsal views (anterior to left) of pdx1 expression at 32 hpf in DMSO-treated wild-type (A), RA-treated wild-type (B), DMSO-treated smo^1a590 mutant (C) and RA-treated smo^1a590 mutant (D) zebrafish embryos. RA treatment (1 μM) from 9-10 hpf induced more pdx1-expressing cells in smo^1a590 mutants (D) than in wild-type embryos (B). Note the migration defect (arrows) of pdx1-expressing cells in RA-treated smo^1a590 mutants (D) as compared with RA-treated wild types (B). The number of embryos displaying similar expression patterns is indicated in each case. Asterisks indicate embryos with mixed genotypes (smo^+/+, smo^+/–, smo^-/-) from smo^1a590 carrier parents.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development