FIGURE

Fig. 1

ID

ZDB-FIG-110207-23

Publication

Du et al., 2011 - Rumba and Haus3 are essential factors for the maintenance of hematopoietic stem/progenitor cells during zebrafish hematopoiesis

Other Figures

All Figure Page

Back to All Figure Page

Fig. 1

rumba^hkz1 and samba^hkz2 are defective in definitive hematopoiesis. (A-B′) WISH of rag1 expression in 6 dpf wild-type (WT) zebrafish siblings (A,A′) and rumba^hkz1-/- (B) and samba^hkz2-/- mutants (B′). The red circles indicate the position of the thymus. (C-F′) WISH of αe1-globin (C-D′) and mpo (E-F′) in 22 hpf wild-type siblings (C,C′,E,E′) and rumba^hkz1-/- (D,F), and samba^hkz2-/- mutants (D′,F′). (G-J′) WISH of αe1-globin (G-H′) and mpo (I-J, I′-J′) in 6 dpf wild-type siblings (G,G′,I,I′) and rumba^hkz1-/- (H,J) and samba^hkz2-/- mutants (H′,J′). Insets in G-J′ show enlarged details of the CHT region. The blue arrowheads indicate the position of the kidney.

Expression Data

Genes:	hbae1.1 mpx rag1
Fish:	AB haus3^hkz2/hkz2 (AB) znf574^hkz1/hkz1 (AB)
Anatomical Terms:	blood erythroid lineage cell blood island myeloid cell head kidney intermediate cell mass of mesoderm erythroid lineage cell myeloid cell post-vent region erythroid lineage cell post-vent region myeloid cell thymus
Stage Range:	26+ somites to Day 6

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	haus3^hkz2/hkz2 (AB) znf574^hkz1/hkz1 (AB)
Observed In:	blood vasculature definitive hemopoiesis primitive hemopoiesis whole organism
Stage Range:	26+ somites to Days 7-13

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development