Fig. 1 rumbahkz1 and sambahkz2 are defective in definitive hematopoiesis. (A-B′) WISH of rag1 expression in 6 dpf wild-type (WT) zebrafish siblings (A,A′) and rumbahkz1-/- (B) and sambahkz2-/- mutants (B′). The red circles indicate the position of the thymus. (C-F′) WISH of αe1-globin (C-D′) and mpo (E-F′) in 22 hpf wild-type siblings (C,C′,E,E′) and rumbahkz1-/- (D,F), and sambahkz2-/- mutants (D′,F′). (G-J′) WISH of αe1-globin (G-H′) and mpo (I-J, I′-J′) in 6 dpf wild-type siblings (G,G′,I,I′) and rumbahkz1-/- (H,J) and sambahkz2-/- mutants (H′,J′). Insets in G-J′ show enlarged details of the CHT region. The blue arrowheads indicate the position of the kidney.
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