FIGURE

Fig. 4

ID

ZDB-FIG-101206-46

Publication

Choy et al., 2010 - A cascade of irx1a and irx2a controls shh expression during retinogenesis

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Fig. 4

irx2a is not required for the neurogenesis of photoreceptors cells in ONL. A–F: Section immunostaining of Zpr1 and Zpr3 in 96-hpf retina. Zpr1 immunostaining of control retina (A) labeled a subset of cone photoreceptors in the ONL. Only a small patch of Zpr1-labeled cells could be detected in the irx1a MO2 morphant retina (B), whereas irx2a MO2 morphants (C) showed similar staining of Zpr1 in the ONL as the control. Zpr3 immunostaining of a control retina (D) labeled rod photoreceptors in the ONL. Similar to Zpr1 staining, a small patch of Zpr3-expressing cells could be detected in irx1a MO2 morphant retina (E) whereas the Zpr3-expressing cells could be observed as normal in irx2a MO2 morphant retina (F).

Expression Data

Antibodies:	zpr-1 zpr-3
Fish:	WT WT + MO2-irx2a WT + MO4-irx1a
Knockdown Reagents:	MO2-irx2a MO4-irx1a
Anatomical Terms:	retinal cone cell retinal rod cell
Stage:	Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO2-irx2a WT + MO4-irx1a
Knockdown Reagents:	MO2-irx2a MO4-irx1a
Observed In:	photoreceptor cell retinal cone cell retinal rod cell
Stage:	Day 4

Phenotype Detail

Acknowledgments

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