FIGURE

Fig. 6

ID

ZDB-FIG-101012-20

Publication

Mei et al., 2010 - Mtmr8 is essential for vasculature development in zebrafish embryos

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Fig. 6

(A-F) The expression of ephrinB2a (A, B) and mtmr8 (C-F) in 26 hpf embryos incubated with DMSO (A, C) or cyclopamine (B, E). (D, F) are magnification of (C, E) in the trunk vasculture. (G-H) Mtmr8 expression in 30 hpf embryos incubated with DMSO (G) or SU5416 (H). (I-J) Vegf165 expression in 26 hpf Cont-MO and Mtmr8 morphant embryos. (K) Mtmr8 expression changes revealed by Q-RT-PCR in embryos treated with different doses of SU5416 and cyclopamine (μM). (L) Vegf165 expression in 26 hpf Cont-MO and Mtmr8 morphant embryos revealed by Q-RT-PCR. (M) Statistical data of different defect phenotypes at 26 hpf in Mtmr8-MO, Mtmr8-MO+dnPKA mRNA, and Mtmr8-MO+vegf121/165 mRNA embryos.

Expression Data

Genes:	efnb2a mtmr8 vegfaa
Fish:	AB AB + MO1-mtmr8
Conditions:	chemical treatment: Cyclopamine chemical treatment: semaxanib
Knockdown Reagent:	MO1-mtmr8
Anatomical Term:	trunk vasculature
Stage Range:	Prim-5 to Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ BMC Dev. Biol.