FIGURE
Fig. 5
- ID
- ZDB-FIG-101007-7
- Publication
- Ramesh et al., 2010 - A genetic model of amyotrophic lateral sclerosis in zebrafish displays phenotypic hallmarks of motoneuron disease
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Fig. 5
Motor neuron loss was observed in G93R os10 spinal cord at the disease end-stage. (A) ChAT immunohistochemistry of anterior spinal cord sections from adult G93R os10 fish and nTg siblings demonstrates reduced numbers of positively labeled motor neurons (denoted by arrows) in end-stage fish compared with controls. (B) ChAT-positive motoneurons (≥10 μm diameter) from anterior spinal cord sections (20 μm thickness) of adult end-stage fish were blinded to genotype and counted (*P<0.0001, n=40 sections per fish, three fish per genotype). Data are mean ± s.e.m. Bar, 200 μm. |
Expression Data
| Gene: | |
|---|---|
| Antibody: | |
| Fish: | |
| Anatomical Term: | |
| Stage: | Adult |
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Observed In: | |
| Stage: | Adult |
Phenotype Detail
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Full text @ Dis. Model. Mech.