FIGURE

Fig. S2

ID

ZDB-FIG-100723-38

Publication

Freisinger et al., 2010 - Regulator of g protein signaling 3 modulates wnt5b calcium dynamics and somite patterning

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Fig. S2

rgs3 impacts segmentation stage calcium dynamics, related to Figure 5. Zebrafish embryos injected with Fura-2 oriented in a lateral posterior view (A) with a focus on the developing somites and tail (boxed region). Ratio images, pseudocolored to represent low Ca²⁺ as blue and high Ca²⁺ as yellow/red (B–J). Representative ratio images of 6 somite stage (B, E and H), 8 somite stage (C, F, and I) and 10 somite stage (D, G and J) embryos. Arrowheads indicate large Ca2+ transients in rgs3 morphant embryos (E–G) that are not observed in Wt (B–D) or wnt5b morphant embryos (H–J). The number of Ca²⁺ transients per hour observed in embryos oriented in a lateral posterior view from 6 to 12 somite stage is represented function of developmental age is represented graphically (K).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO4-wnt5b
Knockdown Reagent:	MO4-wnt5b
Observed In:	Wnt signaling pathway, calcium modulating pathway
Stage Range:	5-9 somites to 10-13 somites

Phenotype Detail

Acknowledgments

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