FIGURE

Fig. 1

ID

ZDB-FIG-100706-21

Publication

Takada et al., 2010 - Identification of genes expressed by zebrafish oligodendrocytes using a differential microarray screen

Other Figures

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Fig. 1

HDAC inhibitor TSA blocks oligodendrocyte formation. Embryos were treated with TSA from 36 hours postfertilization (hpf) to 3 days postfertilization (dpf). A,C,E,G,I: Controls. B,D,F,H,J: Trichostatin A (TSA) treated. A-D: Lateral views of the spinal cord. E-J: Transverse sections of the spinal cord of Tg(olig2:egfp) larvae. A,B: Images of the spinal cord of living Tg(olig2:egfp) larvae at 3 dpf. Asterisks indicate dorsally migrated oligodendrocyte progenitor cells (OPCs). C,D: Expression of mbp mRNA at 3 dpf. E,F: Sox10 antibody labeling (red). Arrows indicate Sox10⁺ olig2:EGFP⁺ OPCs. G,H: HuC antibody labeling (red) showing neurons. I,J: Zrf-1antibody labeling (red) showing radial glia. Scale bars = 60 μm in A,B, 15 μm in E-J. SC, spinal cord; EGFP, enhanced green fluorescent protein.

Expression Data

Gene:	mbpa
Antibodies:	Ab1-elavl Ab1-sox10 zrf-1
Fish:	vu12Tg
Condition:	chemical treatment: pharmaceutical
Anatomical Terms:	neuron oligodendrocyte radial glial cell spinal cord oligodendrocyte
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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