FIGURE

Fig. 3

ID

ZDB-FIG-100128-3

Publication

Tse et al., 2009 - Genome-wide loss-of-function analysis of deubiquitylating enzymes for zebrafish development

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Fig. 3

Comparison of ventral (bmp4, eve1, gata2) and dorsal (chd, gsc) markers expression in morphants of group IV zebrafish DUBs at 50-60% epiboly. Ventral markers (bmp4, eve1 and gata2) and dorsal markers (chd and gsc) expression of group IV morphants at 50-60% epiboly stage, animal pole views, dorsal towards the right. otud4 (B, G, L, Q, V), usp5 (C, H, M, R, W) and usp25 (E, J, O, T, Y) morphants showed narrower expression pattern for ventral markers (A-O) but wider expression pattern of dorsal markers (P-Y). usp15 showed a similar expression pattern (D, I, N, S, X) with control (A, F, K, P, U). Red dot lines indicate the normal expression margin of ventral markers in wild-type embryos.

Expression Data

Genes:	bmp4 chrd eve1 gata2a gsc
Fish:	AB AB + MO1-alg13 AB + MO1-usp5 AB + MO1-usp15 AB + MO1-usp25
Knockdown Reagents:	MO1-alg13 MO1-usp5 MO1-usp15 MO1-usp25
Anatomical Terms:	whole organism dorsal region whole organism ventral margin
Stage Range:	50%-epiboly to Germ-ring

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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