FIGURE

Fig. 2

ID

ZDB-FIG-091215-69

Publication

Rohner et al., 2009 - Duplication of fgfr1 Permits Fgf Signaling to Serve as a Target for Selection during Domestication

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Fig. 2

A Mutation in fgfr1a Causes the spd Phenotype

(A) Schematic view of predicted fgfr1a structure and site of zebrafish mutations.

(B) Nucleotide alteration in fgfr1a^t3R705H and fgfr1a^huW671X.

(C and D) fgfr1a expression in the developing scales and lateral-line organs in wild-type fish (C) and in remaining scales of spd fish (D) (both 10 mm standard length).

(E and F) Phenotype of transheterozygous (fgfr1a^t3R705H/fgfr1a^huW671X) fish (E) showing scale loss similar to spd homozygotes in different genetic backgrounds (F).

Expression Data

Gene:	fgfr1a
Fish:	WT fgfr1a^t2227/t2227
Anatomical Terms:	neuromast scale scale primordium
Stage:	Days 30-44

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	fgfr1a^t2227/t2227 fgfr1a^hu3264/+; fgfr1a^t2227/+
Observed In:	scale skin morphogenesis
Stage:	Days 30-44

Phenotype Detail

Acknowledgments

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