FIGURE
Fig. 1
- ID
- ZDB-FIG-090304-1
- Publication
- Slanchev et al., 2009 - Control of Dead end localization and activity – Implications for the function of the protein in antagonizing miRNA function
- Other Figures
- All Figure Page
- Back to All Figure Page
Fig. 1
Dead end 3′UTR is responsible for targeting of dnd mRNA to the PGCs. (A, B) 1-cell stage embryos injected with GFP mRNA fused to Dnd 3′UTR were subjected to in situ hybridization with GFP anti-sense probe. GFP mRNA is restricted to the PGCs only by the dnd 3′UTR (A), in contrast to the globin driven ubiquitous mRNA expression (B). Accordingly, the GFP protein produced by the fusion mRNA follows the same pattern and is detected by fluorescent microscopy at 24hpf only in the PGCs in the case of dnd UTR (C) or ubiquitously as for globin UTR (D). |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Reprinted from Mechanisms of Development, 126(3-4), Slanchev, K., Stebler, J., Goudarzi, M., Cojocaru, V., Weidinger, G., and Raz, E., Control of Dead end localization and activity – Implications for the function of the protein in antagonizing miRNA function, 270-277, Copyright (2009) with permission from Elsevier. Full text @ Mech. Dev.