FIGURE

Fig. S2

ID

ZDB-FIG-090127-28

Publication

Targoff et al., 2008 - Nkx genes regulate heart tube extension and exert differential effects on ventricular and atrial cell number

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Fig. S2

Splice MOs recapitulate the phenotype resulting from injection of ATG MOs. In situ hybridization depicts expression of vmhc in (A) wild-type and (B) anti-nkx2.5 and anti-nkx2.7 splice MO-injected embryos. Embryos viewed dorsally, anterior to the top, at the 26 hpf stage. The vmhc-expressing portion of the nkx-deficient heart tube is substantially shorter and wider than the vmhc-expressing portion of the wild-type heart tube.

Expression Data

Gene:	myh7
Fish:	WT WT + MO2-nkx2.7 + MO3-nkx2.5
Knockdown Reagents:	MO2-nkx2.7 MO3-nkx2.5
Anatomical Term:	presumptive cardiac ventricle heart tube
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO2-nkx2.7 + MO3-nkx2.5
Knockdown Reagents:	MO2-nkx2.7 MO3-nkx2.5
Observed In:	cardiac ventricle embryonic heart tube development
Stage:	Prim-5

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 322(2), Targoff, K.L., Schell, T., and Yelon, D., Nkx genes regulate heart tube extension and exert differential effects on ventricular and atrial cell number, 314-321, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.