FIGURE

Fig. S3

ID

ZDB-FIG-081222-10

Publication

Osborne et al., 2008 - The spinster homolog, two of hearts, is required for sphingosine 1-phosphate signaling in zebrafish

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Fig. S3

toh Is Expressed Dynamically throughout Development Images of toh expression during early development. toh mRNA is maternally provided as seen at the 8 cell stage (A, dorsal view). In a lateral view at 4 hpf, diffuse toh expression can be seen throughout the blastoderm (B). At 6 hpf (C, lateral view, dorsal to the right), toh expression is upregulated in cells that have undergone involution (arrowhead) and is also expressed in the yolk cell. At 24 hpf (D-G), toh is expressed in distinct domains. In a whole animal lateral view, anterior to the left (D), expression can be seen in the endoderm, which is adjacent to the yolk. In a blow up of the boxed region in panel D, toh expression can be seen in a distinct compartment within the somites (E, arrowhead). In dorsal, anterior (F) and dorsolateral, anterior (G) views, anterior to the left, toh expression can be seen in the heart tube.

Expression Data

Gene:	spns2
Fish:	WT
Anatomical Terms:	blastoderm blastodisc heart tube somite whole organism yolk
Stage Range:	8-cell to Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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