FIGURE

Fig. 4

ID

ZDB-FIG-080904-55

Publication

Kai et al., 2008 - Sphingosine-1-phosphate receptors regulate individual cell behaviours underlying the directed migration of prechordal plate progenitor cells during zebrafish gastrulation

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Fig. 4

slb cells with compromised Mil function undergo involution differently to WT cells. Multi-photon confocal analysis of involution cell behaviour through the shield region. Lateral views of WT embryo (A) and slb embryo injected with 4.3 ng mil-MO (B) at 60% epiboly. In the hypoblast layer of the slb embryo injected with mil-MO, cells are internalised as one- or two-cell thick layers, occasionally with space in between the cells, whereas in the WT embryo hypoblast cells are internalised as approximately three-cell thick layers throughout and are tightly packed. epi, epiblast layer; inv, involution; hyp, hypoblast layer. The orientation of embryos is shown as indicated along the animal (an)-vegetal (vg) axis and the dorsal (dor)-ventral (vent) axis.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	wnt11f2^tx226/tx226 + MO1-s1pr2
Knockdown Reagent:	MO1-s1pr2
Observed In:	involution involved in gastrulation with mouth forming second
Stage:	Shield

Phenotype Detail

Acknowledgments

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