FIGURE

Fig. 2

ID

ZDB-FIG-080411-58

Publication

Webb et al., 2008 - psoriasis regulates epidermal development in zebrafish

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Fig. 2

psoriasis embryos fail to cease epidermal proliferation at 80 hours postfertilization (hpf). A-C: The epidermis of wild-type embryos is 5′-bromodeoxyuridine (BrdU) -negative (B) at 80 hpf, indicating cessation of epidermal proliferation late in embryogenesis. D-F: Epidermal cells in psoriasis mutants are BrdU-positive at 80 hpf (E). G-I: The level of proliferation observed in psoriasis embryos is similar to that observed in 48 hr wild-type embryos (H). Anterior is to the left. Brightfield images are shown in A, D, and G, BrdU-positive cells are green in B, E, and H. C, F, and I are merged brightfield and fluorescent images. J: Quantification of cell proliferation at 48, 60, and 72 hpf. Scale bars = 50 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	atp1b1a^m14/m14 (AB)
Observed In:	cell population proliferation epidermal cell
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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