FIGURE

Fig. 1

ID

ZDB-FIG-080301-1

Publication

Sarmah et al., 2007 - A role for the inositol kinase Ipk1 in ciliary beating and length maintenance

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Fig. 1

ipk1 knockdown reduces normal ciliary beating and length. (A and B) Schematic diagrams (A) and kymographs (B) showing trajectory of a cilium in uninjected, ipk1 ^MO1-injected, ipk1 ^MO1 plus wild-type ipk1 mRNA-injected, or ipk1 ^MO1 plus kinase-dead (kd) ipk1 mRNA-injected embryos. (C) Graphs for measurements of ciliary length from individual embryos (green), with the mean ciliary length (far right, purple) determined from multiple independent measurements for KV (n > 26), pronephric duct (n > 13), and spinal canal (n > 14) cilia. (D) Representative images of KV cilia (red) from embryos injected with 10 ng of either control MO or ipk1 ^MO1. n, number of cilia measured per embryo.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-ippk
Knockdown Reagent:	MO1-ippk
Observed In:	central canal cilium Kupffer's vesicle cilium pronephric duct cilium
Stage Range:	5-9 somites to Prim-15

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA