FIGURE

Fig. 4

ID

ZDB-FIG-071019-36

Publication

Pei et al., 2007 - An early requirement for maternal FoxH1 during zebrafish gastrulation

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Fig. 4

Down-regulation of keratins and up-regulation of cell cycle genes in FoxH1 morphants. (A, B, I and J) Loss of cyt1 expression in FoxH1-depleted embryos at 40% epiboly. Panels A and I are lateral views, panels B and J are animal pole views. Arrowheads in panel A point to the superficial expression of cyt1 in the enveloping layer (EVL). (C–F; K–N) Reduced expression of four other keratins in FoxH1 morphants at the 40% epiboly stage. (G–H; O–P) Increased expression of her5 and cdc14 expression in FoxH1 morphants at the 50% epiboly stage. Panels C–H and K–P are animal pole views. (Q–Z) Recovery of most keratins in FoxH1 morphants at bud stage. Panels Q–Z are dorsal views. Abbreviations: FH1, FoxH1; ctrl, control.

Expression Data

Genes:	cdc14b cyt1 her5 krt4 krt5 krt8 krt18a.1
Fish:	WT WT + MO1-foxh1
Knockdown Reagent:	MO1-foxh1
Anatomical Terms:	EVL periderm
Stage Range:	30%-epiboly to Bud

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 310(1), Pei, W., Noushmehr, H., Costa, J., Ouspenskaia, M.V., Elkahloun, A.G., and Feldman, B., An early requirement for maternal FoxH1 during zebrafish gastrulation, 10-22, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.