Gene

cdc14b

ID

ZDB-GENE-040426-820

Name

cell division cycle 14B

Symbol

cdc14b Nomenclature History

Previous Names

cdc14a (1)
zgc:55844 (1)

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Description

Predicted to have protein serine/threonine phosphatase activity and protein tyrosine phosphatase activity. Involved in cilium assembly. Localizes to condensed chromosome; nucleolus; and spindle. Is expressed in EVL and proliferative region. Orthologous to several human genes including CDC14B (cell division cycle 14B).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:55844 (9 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 11 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cdc14b Human Ortholog

No data available

Associated With cdc14b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR016130	Protein-tyrosine phosphatase, active site
Domain	IPR000340	Dual specificity phosphatase, catalytic domain
Domain	IPR000387	Tyrosine-specific protein phosphatases domain
Domain	IPR003595	Protein-tyrosine phosphatase, catalytic
Domain	IPR020422	Dual specificity protein phosphatase domain
Domain	IPR029260	Dual specificity/tyrosine protein phosphatase, N-terminal
Domain	IPR044506	Dual-specificity phosphatase CDC14, C-terminal
Family	IPR050561	Protein Tyrosine Phosphatase
Homologous_superfamily	IPR029021	Protein-tyrosine phosphatase-like

Domain Details Per Protein

Protein	Length	Dual specificity phosphatase, catalytic domain	Dual-specificity phosphatase CDC14, C-terminal	Dual specificity protein phosphatase domain	Dual specificity/tyrosine protein phosphatase, N-terminal	Protein Tyrosine Phosphatase	Protein-tyrosine phosphatase, active site	Protein-tyrosine phosphatase, catalytic	Protein-tyrosine phosphatase-like	Tyrosine-specific protein phosphatases domain
UniProtKB:F8W2B2 InterPro	476
UniProtKB:A0A8M2BE48 InterPro	519
UniProtKB:A0A8M9QII0 InterPro	419
UniProtKB:A0A8M9Q9K5 InterPro	451
UniProtKB:A0A8M2BE70 InterPro	508
UniProtKB:A0A8M2BE31 InterPro	498
UniProtKB:Q7ZVN3 InterPro	404

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
aberrant processed transcript	cdc14b-203 (1) Ensembl	Ensembl	851 nt	Select Tool
antisense	ottdart00000059745 (1) Ensembl	Ensembl	1,356 nt	Select Tool
mRNA	cdc14b-202 (1) Ensembl	Ensembl	863 nt	Select Tool
mRNA	cdc14b-204 (1) Ensembl	Ensembl	868 nt	Select Tool
mRNA	cdc14b-205 (1) Ensembl	Ensembl	1,484 nt	Select Tool
mRNA	cdc14b-206 (1) Ensembl	Ensembl	2,055 nt	Select Tool
mRNA	cdc14b-208 (1) Ensembl	Ensembl	1,217 nt	Select Tool ZFIN BLAST
ncRNA	cdc14b-005 (1) Ensembl	Ensembl	782 nt	Select Tool
ncRNA	cdc14b-006 (1) Ensembl	Ensembl	1,030 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations