FIGURE

Fig. 6

ID

ZDB-FIG-070813-5

Publication

Gourronc et al., 2007 - Nodal activity around Kupffer's vesicle depends on the T-box transcription factors notail and spadetail and on notch signaling

Other Figures

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Fig. 6

Effects of the γ-secretase inhibitor DAPT on charon and perinodal southpaw expression. A-F: Arrowheads: tailbud/KV region. Dig-cha probe. +DAPT: treated with 100 μM DAPT dissolved in DMSO. +DMSO: treated with 1% DMSO. A: Two to 3 s DAPT-treated embryo with reduced charon expression relative to DMSO control. B: Four to 6 s. Dorsal view of Kupffer′s Vesicle (arrowhead). C,D: Examples of mid-somite stage embryos, treated with DMSO alone or with DAPT. E,F: Enlarged views of embryos from C,D sets. E: Example of DAPT-treated embryo with no charon expression. F: Example of DAPT-treated embryo with reduced charon expression. G,H: Seventeen to 18 s. Dig-spaw probe. G: Dorsal view, head to upper right. Arrows: spaw expression in the LPM. H: Dorsal view of tail. Arrowheads: perinodal spaw.

Expression Data

Genes:	dand5 spaw
Fish:	WT
Condition:	chemical treatment: DAPT
Anatomical Terms:	forerunner cell group Kupffer's vesicle lateral plate mesoderm
Stage Range:	1-4 somites to 14-19 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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