FIGURE

Fig. 7

ID

ZDB-FIG-070501-12

Publication

Baye et al., 2007 - The disarrayed mutation results in cell cycle and neurogenesis defects during retinal development in zebrafish

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Fig. 7

Genetic mosaic analysis of disarrayed retinal cells. Genetic mosaic retinas at 72 hpf where donor cells were lineage-labeled using biotin conjugated dextran (brown). (A) disarrayed mutant cells in a disarrayed mutant host embryo. Note reduced morphological differentiation and lamination of cells. (B) Wild-type cells in a wild-type host embryo. (C) disarrayed mutant cells in a wild-type host embryo. The disarrayed cells show wild-type morphology and lamination in the wild-type environment (compare B and C). For example, morphological rescue of photoreceptor elongation can be seen (C, arrows). (D) Wild-type cells in a disarrayed mutant embryo. Small wild-type cell clones resemble mutant cells as they appear delayed in morphological differentiation and lamination (dorsal, arrowheads). Wild-type cells in clones with greater donor mosaicism have normal morphological differentiation and rescue adjacent disarrayed mutant cells (ventral, arrows). The number of mosaic embryos examined: n = 2 disarrayed into disarrayed, n = 5 wild-type into wild-type, n = 9 disarrayed into wild-type, n = 8 wild-type into disarrayed. Each embryo contained multiple cell clones.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ BMC Dev. Biol.