FIGURE

Fig. 10

ID

ZDB-FIG-070309-26

Publication

Svetic et al., 2007 - Sdf1a patterns zebrafish melanophores and links the somite and melanophore pattern defects in choker mutants

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Fig. 10

Morpholino-mediated knock-down of sdf1a generates melanophore patterning defects in 55 hpf embryos. (A-D) Fixed cho mutant embryos (B,D) and WT siblings (A,C) with (C,D) or without (A,B) sdf1a morpholino. Note the decreased numbers of melanophores in the WT lateral stripe (arrow) and the cho collar (arrowhead) after morpholino injection. Scale bar: 375 μm. (E,F) Quantitation of these defects. (E) Lateral pathway collar melanophores of cho mutant embryos. (F) Lateral stripe melanophores of WT siblings. Bar graphs show mean±s.e. melanophore counts per embryo; number of embryos is indicated at base of bar. WT and cho mutants were identified by their anterior trunk myotome phenotypes. Reduction of cho mutant collar and WT lateral stripe melanophores were both highly significant; ^***, Student's t-test P<0.0001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	meox1^tm26/tm26 WT + MO2-cxcl12a meox1^tm26/tm26 + MO2-cxcl12a
Knockdown Reagent:	MO2-cxcl12a
Observed In:	melanocyte melanophore stripe melanocyte
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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